| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Is Meddas | city | Sardegna | Italy | 39.15 | 8.68 | 830 | 3479 |
| Is Morus | city | Sardegna | Italy | 38.94 | 8.94 | 0 | 3284 |
| Is Pratzas | city | Sardegna | Italy | 39.68 | 8.99 | 830 | 4799 |
| Is Pratzas/Las Plassas | city | Sardegna | Italy | 39.68 | 8.99 | 830 | 4799 |
| Is Traias | city | Sardegna | Italy | 39.13 | 9.54 | 0 | 2003 |
| Isca | city | Calabria | Italy | 38.60 | 16.52 | 830 | 9340 |
| Isca Romana | city | Calabria | Italy | 39.15 | 16.37 | 3710 | 9237 |
| Isca dell'Ionio | city | Calabria | Italy | 38.60 | 16.52 | 830 | 9340 |
| Isca dello Ionio | city | Calabria | Italy | 38.60 | 16.52 | 830 | 9340 |
| Isca dell’Ionio | city | Calabria | Italy | 38.60 | 16.52 | 830 | 9340 |
| Isca sull'Ionio | city | Calabria | Italy | 38.60 | 16.52 | 830 | 9340 |
| Isca sullo Ionio | city | Calabria | Italy | 38.60 | 16.52 | 830 | 9340 |
| Isca sull’Ionio | city | Calabria | Italy | 38.60 | 16.52 | 830 | 9340 |
| Iscalepranu | city | Sardegna | Italy | 39.62 | 9.35 | 1102 | 2623 |
| Iscaramano | city | Calabria | Italy | 39.15 | 16.37 | 3710 | 9237 |
| Ischellini | city | Calabria | Italy | 39.43 | 16.77 | 1669 | 2280 |
| Ischettini | city | Calabria | Italy | 39.43 | 16.77 | 1669 | 2280 |
| Ischia | city | Campania | Italy | 40.73 | 13.95 | 0 | 35442 |
| Ischia Porto | city | Campania | Italy | 40.73 | 13.95 | 0 | 35442 |
| Ischia di Castro | city | Lazio | Italy | 42.55 | 11.75 | 1669 | 3510 |
| Ischiaromana | city | Calabria | Italy | 39.15 | 16.37 | 3710 | 9237 |
| Ischitella | city | Puglia | Italy | 41.90 | 15.90 | 1669 | 7257 |
| Iscla | city | Campania | Italy | 40.73 | 13.95 | 0 | 35442 |
| Iscroca | city | Sardegna | Italy | 39.70 | 9.12 | 1669 | 4719 |
| Iscroca/Escolca | city | Sardegna | Italy | 39.70 | 9.12 | 1669 | 4719 |
| Iselle | city | Piemonte | Italy | 46.20 | 8.20 | 4445 | 4413 |
| Iseo | city | Lombardia | Italy | 45.65 | 10.05 | 1830 | 25310 |
| Isernia | city | Molise | Italy | 41.60 | 14.23 | 1669 | 21557 |
| Isiata | city | Veneto | Italy | 45.61 | 12.61 | 9 | 34877 |
| Isineɖɖu | city | Sicilia | Italy | 37.93 | 14.00 | 2509 | 3057 |
| Isla Favignana | city | Sicilia | Italy | 37.93 | 12.33 | 232 | 2224 |
| Isla de Capri | city | Campania | Italy | 40.55 | 14.23 | 0 | 13007 |
| Isla del Giglio | city | Toscana | Italy | 42.37 | 10.90 | 830 | 1326 |
| Isneddu | city | Sicilia | Italy | 37.93 | 14.00 | 2509 | 3057 |
| Isnello | city | Sicilia | Italy | 37.93 | 14.00 | 2509 | 3057 |
| Isola | city | Abruzzo | Italy | 42.50 | 13.67 | 1833 | 5207 |
| Isola | city | Calabria | Italy | 38.97 | 17.08 | 291 | 13412 |
| Isola | city | Lombardia | Italy | 46.43 | 9.32 | 5869 | 1155 |
| Isola | city | Valle d'Aosta | Italy | 45.70 | 7.70 | 2509 | 7104 |
| Isola | city | Emilia-Romagna | Italy | 44.43 | 10.17 | 2509 | 1776 |
| Isola | city | Italy | 44.18 | 9.92 | 170 | 31339 | |
| Isola | city | Liguria | Italy | 44.13 | 9.83 | 124 | 86107 |
| Isola | city | Marche | Italy | 43.33 | 13.12 | 1669 | 5980 |
| Isola | city | Toscana | Italy | 43.27 | 11.38 | 830 | 21665 |
| Isola | city | Friuli-Venezia Giulia | Italy | 46.26 | 13.17 | 1732 | 17167 |
| Isola Bella | city | Lazio | Italy | 41.55 | 12.80 | 127 | 23775 |
| Isola Capo Rizzuto | city | Calabria | Italy | 38.97 | 17.08 | 291 | 13412 |
| Isola Comacina | city | Lombardia | Italy | 45.97 | 9.17 | 830 | 10711 |
| Isola Dovarese | city | Lombardia | Italy | 45.17 | 10.30 | 95 | 8007 |
| Isola Farnese | city | Lazio | Italy | 42.02 | 12.38 | 328 | 149100 |
| Isola Fossara | city | Umbria | Italy | 43.43 | 12.73 | 1669 | 2897 |
| Isola Pescaroli | city | Lombardia | Italy | 45.05 | 10.17 | 68 | 7005 |
| Isola San Biagio | city | Marche | Italy | 42.90 | 13.30 | 2811 | 1224 |
| Isola Sant'Antonio | city | Piemonte | Italy | 45.03 | 8.85 | 223 | 8349 |
| Isola Santa | city | Toscana | Italy | 44.07 | 10.32 | 1938 | 3584 |
| Isola Sant’Antonio | city | Piemonte | Italy | 45.03 | 8.85 | 223 | 8349 |
| Isola Vicentina | city | Veneto | Italy | 45.63 | 11.42 | 301 | 27347 |
| Isola d'Arbia | city | Toscana | Italy | 43.27 | 11.38 | 830 | 21665 |
| Isola d'Ischia | city | Campania | Italy | 40.73 | 13.95 | 0 | 35442 |
| Isola del Cantone | city | Liguria | Italy | 44.65 | 8.95 | 1043 | 5979 |
| Isola del Giglio | city | Toscana | Italy | 42.37 | 10.90 | 830 | 1326 |
| Isola del Gran Sasso | city | Abruzzo | Italy | 42.50 | 13.67 | 1833 | 5207 |
| Isola del Gran Sasso d'Italia | city | Abruzzo | Italy | 42.50 | 13.67 | 1833 | 5207 |
| Isola del Gran Sasso d’Italia | city | Abruzzo | Italy | 42.50 | 13.67 | 1833 | 5207 |
| Isola del Liri | city | Lazio | Italy | 41.68 | 13.57 | 866 | 34220 |
| Isola del Piano | city | Marche | Italy | 43.73 | 12.78 | 830 | 5811 |
| Isola della Scala | city | Veneto | Italy | 45.27 | 11.00 | 68 | 13404 |
| Isola delle Femmine | city | Sicilia | Italy | 38.20 | 13.25 | 1082 | 111251 |
| Isola di Capo Rizzuto | city | Calabria | Italy | 38.97 | 17.08 | 291 | 13412 |
| Isola di Fano | city | Marche | Italy | 43.65 | 12.85 | 830 | 7696 |
| Isola di Levanzo | city | Sicilia | Italy | 37.98 | 12.33 | 0 | 1594 |
| Isola di Liri | city | Lazio | Italy | 41.68 | 13.57 | 866 | 34220 |
| Isola di Pianosa | city | Toscana | Italy | 42.58 | 10.08 | 6 | 941 |
| Isolabona | city | Liguria | Italy | 43.88 | 7.63 | 830 | 8862 |
| Isolaccia | city | Lombardia | Italy | 46.48 | 10.28 | 5869 | 1718 |
| Isolalunga | city | Liguria | Italy | 43.90 | 7.95 | 285 | 29598 |
| Isolate | city | Lombardia | Italy | 46.43 | 9.32 | 5869 | 1155 |
| Isolato | city | Lombardia | Italy | 46.43 | 9.32 | 5869 | 1155 |
| Isolaz | city | Valle d'Aosta | Italy | 45.70 | 7.70 | 2509 | 7104 |
| Isole San Nicola | city | Puglia | Italy | 42.12 | 15.52 | 0 | 367 |
| Isolella | city | Veneto | Italy | 45.00 | 12.00 | 16 | 8702 |
| Isollaz | city | Valle d'Aosta | Italy | 45.70 | 7.70 | 2509 | 7104 |
| Isorella | city | Lombardia | Italy | 45.30 | 10.32 | 147 | 15348 |
| Ispica | city | Sicilia | Italy | 36.78 | 14.92 | 88 | 19589 |
| Ispra | city | Lombardia | Italy | 45.82 | 8.62 | 830 | 26819 |
| Issime | city | Valle d'Aosta | Italy | 45.68 | 7.85 | 3349 | 1425 |
| Issiria | city | Sardegna | Italy | 40.02 | 9.23 | 3710 | 3937 |
| Issogne | city | Valle d'Aosta | Italy | 45.65 | 7.68 | 2509 | 6038 |
| Istersili | city | Sardegna | Italy | 39.78 | 9.29 | 2916 | 1315 |
| Istersili/Esterzili | city | Sardegna | Italy | 39.78 | 9.29 | 2916 | 1315 |
| Isthintini | city | Sardegna | Italy | 40.94 | 8.23 | 0 | 5256 |
| Isthintini/Stintino | city | Sardegna | Italy | 40.94 | 8.23 | 0 | 5256 |
| Istia | city | Toscana | Italy | 42.78 | 11.18 | 95 | 17718 |
| Istia D'Ombrone-Le Stiacciole | city | Toscana | Italy | 42.78 | 11.18 | 95 | 17718 |
| Istia d'Ombrone | city | Toscana | Italy | 42.78 | 11.18 | 95 | 17718 |
| Istia d’Ombrone | city | Toscana | Italy | 42.78 | 11.18 | 95 | 17718 |
| Istintino | city | Sardegna | Italy | 40.94 | 8.23 | 0 | 5256 |
| Istintinu | city | Sardegna | Italy | 40.94 | 8.23 | 0 | 5256 |
| Istonio | city | Abruzzo | Italy | 42.12 | 14.70 | 311 | 28596 |
| Istrago | city | Friuli-Venezia Giulia | Italy | 46.13 | 12.88 | 406 | 13169 |
| Istrana | city | Veneto | Italy | 45.68 | 12.10 | 101 | 27753 |
| Isula di u Gigliu | city | Toscana | Italy | 42.37 | 10.90 | 830 | 1326 |
| Isula e Capri | city | Campania | Italy | 40.55 | 14.23 | 0 | 13007 |
| Isule | city | Friuli-Venezia Giulia | Italy | 46.26 | 13.17 | 1732 | 17167 |
| Isule Murusine | city | Friuli-Venezia Giulia | Italy | 45.77 | 13.43 | 16 | 15337 |
| Isìles | city | Piemonte | Italy | 45.10 | 6.93 | 4189 | 1234 |